Tnfrsf4 - TNF receptor superfamily member 4 Gene

Also Known as Ox40; Txgp1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25572

Summary

Predicted to enable tumor necrosis factor-activated receptor activity. Involved in T cell proliferation. Located in cell surface. Human ortholog(s) of this gene implicated in immunodeficiency 16. Orthologous to human TNFRSF4 (TNF Receptor Superfamily member 4). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf4 Products (1)

mRNA Protein Name
NM_013049.1 NP_037181.1 tumor necrosis factor receptor superfamily member 4 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in T cell proliferation IMP
IMP: Inferred from mutant phenotype
2828930 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IMP
IMP: Inferred from mutant phenotype
2828930 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor receptor superfamily member 4

  • MRC OX40

  • OX40 antigen

  • OX40L receptor

  • Tax-transcriptionally activated glycoprotein 1

  • tumor necrosis factor (ligand) superfamily member 4

  • tumor necrosis factor receptor superfamily, member 4

  • tumor necrosis factor superfamily, member 4

Recombinant Tnfrsf4 Proteins

Cat. No. Product Name Accession Purity
HY-P74660 OX40 Ligand/TNFSF4 Protein, Rat (HEK293, Fc) P15725 (V20-P210) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991614 IBI356 Inhibitor / Phase 2

Pre-clinical Phase

Inhibitory Antibodies (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992132 Solaprubart Inhibitor 99.59% Unkown
HY-P992415 MSB013 Inhibitor / Unkown
HY-P992435 OX118 Inhibitor / Unkown
HY-P992368 HLX51 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfrsf4 NCBI NCBI:7293