Cckbr - cholecystokinin B receptor Gene

Rattus norvegicus

Also known as Cck2r; Cholrec

Gene ID: 25706 | Gene type: protein coding

About Cckbr

Primary_assembly 1: 159,771,733-159,814,881 forward strand.mRatBN7.2:CM026974.1

This gene has 3 transcripts (splice variants), 268 orthologues, 16 paralogues and is associated with 12 phenotypes. Restricted expression toward (RPKM 39.4).

Summary

Cholecystokinin was one of the first gastrointestinal Peptides discovered in the mammalian brain. Cholecystokinin receptors are members of the G protein-coupled receptor superfamily, stimulating phosphatidylinositol turnover and intracellular calcium mobilization. This gene encodes a Cholecystokinin Receptor of the B subtype. These receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. [provided by RefSeq, Jul 2008]

Cckbr Products(1)

mRNA	Protein	Name
NM_013165.3	NP_037297.2	gastrin/cholecystokinin type B receptor

Cckbr Protein Structure

7tm_GPCRs

0
100
200
300
400
452 a.a.

Protein Preferred Names

Protein Names

gastrin/cholecystokinin type B receptor

CCK-B receptor	CCK-BR
CCK2 receptor	CCK2-R
cholecystokinin-2 receptor

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-A0261	Pentagastrin	Activator	99.97%	Unkown

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P1097	Gastrin I, human		99.93%	Unkown
HY-106840	L-365260	Antagonist	99.93%	Unkown
HY-111313	JNJ-26070109	Antagonist	/	Unkown
HY-129810	PD 135158	Antagonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cckbr	NCBI	NCBI:887

Name
Email *

	Sorry, but the email address you supplied was invalid.