1. GPCR/G Protein
    Neuronal Signaling
  2. Cholecystokinin Receptor
  3. Gastrazole

Gastrazole (Synonyms: JB95008)

Cat. No.: HY-19445
Handling Instructions

Gastrazole (JB95008) is potent and selective CCK2/gastrin receptor antagonist. Gastrazole can decrease the level of gastric acid. Gastrazole inhibits the Gastrin-stimulated growth of pancreatic cancer.

For research use only. We do not sell to patients.

Gastrazole Chemical Structure

Gastrazole Chemical Structure

CAS No. : 862583-15-1

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Description

Gastrazole (JB95008) is potent and selective CCK2/gastrin receptor antagonist. Gastrazole can decrease the level of gastric acid. Gastrazole inhibits the Gastrin-stimulated growth of pancreatic cancer[1][2].

IC50 & Target

CCK2/gastrin receptor[1]

In Vivo

Gastrazole (0.15-3 μmol/kg; i.v.) dose-dependently inhibits the Pentagastrin-stimulated gastric acid secretion[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats with a gastric fistula[2]
Dosage: 0.15, 0.3, 3 mg/kg
Administration: Intravenous administration
Result: Dose-dependently inhibited Pentagastrin-stimulation acid secretion by maximally 73%.
Molecular Weight

687.63

Formula

C₃₄H₃₂FN₅Na₂O₇

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Gastrazole
Cat. No.:
HY-19445
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