NOCT - nocturnin Gene

Also Known as NOC; CCR4L; Ccr4c; CCRN4L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25819

About NOCT

Cytogenetic location: 4q31.1 Genomic coordinates (GRCh38): 4:139,015,781-139,045,939 (from NCBI)

This gene has 3 transcripts (splice variants), 264 orthologues and 5 paralogues. Broad expression in bone marrow (RPKM 15.3), liver (RPKM 6.4) and 18 other tissues.

Summary

The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. [provided by RefSeq, Jul 2008]

NOCT Products (1)

mRNA Protein Name
NM_012118.4 NP_036250.2 nocturnin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables NADP phosphatase activity IDA
IDA: Inferred from direct assay
31147539 GOA
enables NADPH phosphatase activity IDA
IDA: Inferred from direct assay
31147539 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Biological Process GO Annotation Evidence References Source
involved in NADP metabolic process IDA
IDA: Inferred from direct assay
31147539 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
31147539 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NOCT Protein Structure

Exo_endo_phos

Exo_endo_phos: Endonuclease/Exonuclease/phosphatase family (146 - 414)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 431 a.a.
Protein Preferred Names Protein Names

nocturnin

  • CCR4 carbon catabolite repression 4-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09402 NOCT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22263 Noct Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28785 Noct Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris NOCT VGNC VGNC:43876
Mus musculus NOCT MGD MGI:109382
Felis catus NOCT VGNC VGNC:63848
Bos taurus NOCT VGNC VGNC:32149
Rattus norvegicus NOCT RGD RGD:1587344
Macaca mulatta NOCT VGNC VGNC:100256
Others NOCT NCBI