F7 - coagulation factor VII Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 260320

Summary

Enables endopeptidase activity and signaling receptor binding activity. Involved in several processes, including response to anticoagulant; response to peptide hormone; and response to thyroxine. Located in extracellular space and vesicle. Used to study asthma; diabetes mellitus; and type 2 diabetes mellitus. Biomarker of several diseases, including bilirubin metabolic disorder; familial hyperlipidemia; hypertension; hypothyroidism; and prothrombin deficiency. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebral infarction; diabetes mellitus (multiple); factor VII deficiency; and obesity. Orthologous to human F7 (coagulation factor VII). [provided by Alliance of Genome Resources, Apr 2022]

F7 Products (1)

mRNA Protein Name
NM_152846.2 NP_690059.1 coagulation factor VII precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables endopeptidase activity IDA
IDA: Inferred from direct assay
12757778 RGD
enables signaling receptor binding IPI
IPI: Inferred from physical interaction
18315926 RGD
Biological Process GO Annotation Evidence References Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
14724430 RGD
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
2607889 RGD
involved in positive regulation of blood coagulation IDA
IDA: Inferred from direct assay
12757778 RGD
involved in response to 2,3,7,8-tetrachlorodibenzodioxine IEP
IEP: Inferred from expression pattern
10901669 RGD
involved in response to Thyroid stimulating hormone IEP
IEP: Inferred from expression pattern
21382270 RGD
involved in response to astaxanthin IDA
IDA: Inferred from direct assay
22309505 RGD
involved in response to carbon dioxide IEP
IEP: Inferred from expression pattern
26855512 RGD
involved in response to cholesterol IDA
IDA: Inferred from direct assay
15670042 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
20838740 RGD
involved in response to estrogen IEP
IEP: Inferred from expression pattern
2821645 RGD
involved in response to genistein IEP
IEP: Inferred from expression pattern
20838740 RGD
involved in response to growth hormone IEP
IEP: Inferred from expression pattern
7493602 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
18336749 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
9155722 RGD
involved in response to nutrient levels IDA
IDA: Inferred from direct assay
11880553 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
11776312 RGD
involved in response to thyroid hormone IEP
IEP: Inferred from expression pattern
21382270 RGD
involved in response to thyrotropin-releasing hormone IEP
IEP: Inferred from expression pattern
21382270 RGD
involved in response to thyroxine IEP
IEP: Inferred from expression pattern
21382270 RGD
involved in response to vitamin K IEP
IEP: Inferred from expression pattern
3379837 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
14724430 RGD
located in vesicle IDA
IDA: Inferred from direct assay
4307182 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coagulation factor VII

  • serum prothrombin conversion accelerator

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (17)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-113437A 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium 98.0% Unkown
HY-122678 LQZ-7F 97.44% Unkown
HY-W250541 Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH 98.10% Unkown
HY-156095 F7H Inhibitor 99.95% Unkown
HY-113437 1,2-Dipalmitoyl-sn-glycerol 3-phosphate / Unkown
HY-113437AS 1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium 99.0% Unkown
HY-W079257 Desamino lenalidomide-7-F ≥98.0% Unkown
HY-146033 HPV18-IN-1 Inhibitor / Unkown
HY-148696A Gly-Cyclopropane-Exatecan Inhibitor / Unkown
HY-RS04116 E2F7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04645 F7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-46572 Benzyl 2-cyclopropyl-2-hydroxyacetate 98.43% Unkown
HY-RS16932 F7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18926 E2f7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23375 F7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25416 E2f7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W460228 Desamino lenalidomide-4-F-7-Br 99.90% Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991703 Mocertatug Inhibitor 98% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens F7 NCBI NCBI:2155