Soat2 - sterol O-acyltransferase 2 Gene

Also Known as Acat-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 266770

Summary

Enables sterol O-acyltransferase activity. Involved in Cholesterol metabolic process and response to nutrient. Located in endoplasmic reticulum. Used to study end stage renal disease. Biomarker of nephrotic syndrome. Human ortholog(s) of this gene implicated in coronary artery disease and hepatocellular carcinoma. Orthologous to human SOAT2 (sterol O-acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Soat2 Products (1)

mRNA Protein Name
NM_153728.3 NP_714950.3 sterol O-acyltransferase 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables sterol O-acyltransferase activity IDA
IDA: Inferred from direct assay
12217884 RGD
Biological Process GO Annotation Evidence References Source
involved in cholesterol metabolic process IDA
IDA: Inferred from direct assay
12217884 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
12563020 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sterol O-acyltransferase 2

  • acyl-CoA:cholesterol acyltransferase 2

  • acyl-coenzyme A:cholesterol acyltransferase 2

  • cholesterol acyltransferase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-117832 Pyripyropene A Inhibitor 99.37% Unkown
HY-RS13550 SOAT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19037 Soat2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25526 Soat2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Soat2 NCBI NCBI:8435