Nit1 - nitrilase 1 Gene

Also Known as ESTM30

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27045

Summary

Enables deaminated glutathione amidase activity. Involved in cellular amide catabolic process. Located in mitochondrion. Is expressed in several structures, including genitourinary system; liver; mammary gland; musculature; and spleen. Orthologous to human NIT1 (nitrilase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nit1 Products (2)

mRNA Protein Name
NM_001242580.1 NP_001229509.1 deaminated glutathione amidase isoform 2
NM_012049.2 NP_036179.1 deaminated glutathione amidase isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables deaminated glutathione amidase activity IDA
IDA: Inferred from direct assay
28373563 MGI
Biological Process GO Annotation Evidence References Source
involved in amide catabolic process IDA
IDA: Inferred from direct assay
28373563 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
28373563 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
28373563 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

deaminated glutathione amidase

  • dGSH amidase

  • nitrilase homolog 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P10622 SHLP-3 Inhibitor / Unkown
HY-P10625 SHLP-6 / Unkown
HY-RS09310 NIT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19359 Nit1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25851 Nit1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nit1 NCBI NCBI:4817