Chaf1a - chromatin assembly factor 1, subunit A (p150) Gene

Also Known as p150; CAF-1; Cac1p

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27221

Summary

Predicted to enable chromo shadow domain binding activity and identical protein binding activity. Predicted to be involved in DNA replication-dependent chromatin assembly and nucleosome assembly. Predicted to act upstream of or within DNA repair and DNA replication. Predicted to be located in chromatin. Predicted to be part of CAF-1 complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in colon cancer; high grade glioma; neuroblastoma; and systemic lupus erythematosus. Orthologous to human CHAF1A (chromatin assembly factor 1 subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Chaf1a Products (1)

mRNA Protein Name
NM_013733.3 NP_038761.1 chromatin assembly factor 1 subunit A

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10747027 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chromatin assembly factor 1 subunit A

  • CAF-1 subunit A

  • CAF-I 150 kDa subunit

  • CAF-I p150

  • CAF-Ip150

  • chromatin assembly factor I p150 subunit

Chaf1a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Chaf1a Q9QWF0 Gfi1 Mus musculus P70338
IF
21570500
Intra
Chaf1a Q9QWF0 Gfi1 Mus musculus P70338
Anti Bait CoIP
21570500
Intra
Chaf1a Q9QWF0 Cbx1 Mus musculus P83917
NMR
10747027
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02594 CHAF1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21836 Chaf1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28352 Chaf1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chaf1a NCBI NCBI:10036