RNF149 - ring finger protein 149 Gene

Also Known as DNAPTP2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 284996

About RNF149

This gene has 6 transcripts (splice variants), 128 orthologues and 9 paralogues. Ubiquitous expression in bone marrow (RPKM 14.1), appendix (RPKM 12.5) and 25 other tissues.

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within cellular response to xenobiotic stimulus; negative regulation of MAPK cascade; and regulation of protein stability. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

RNF149 Products (1)

mRNA Protein Name
NM_173647.4 NP_775918.2 E3 ubiquitin-protein ligase RNF149 precursor

RNF149 Protein Structure

PA

PA: PA domain (110 - 173)

zf-RING_2

zf-RING_2: Ring finger domain (268 - 310)

  • 0
  • 100
  • 200
  • 300
  • 400 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF149

  • DNA polymerase-transactivated protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12057 RNF149 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21188 Rnf149 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27704 Rnf149 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RNF149 VGNC VGNC:34029
Mus musculus RNF149 MGD MGI:2677438
Rattus norvegicus RNF149 RGD RGD:1308460
Macaca mulatta RNF149 VGNC VGNC:106213
Others RNF149 NCBI