2. Gene
  3. Smyd2 - SET and MYND domain containing 2 Gene

Smyd2 - SET and MYND domain containing 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as HSKM-B

Gene ID: 289372 | Gene type: protein coding

About Smyd2

Primary_assembly 13: 101,425,273-101,466,576 reverse strand.mRatBN7.2:CM026986.1

This gene has 1 transcript (splice variant), 229 orthologues, 5 paralogues and is associated with 3 phenotypes. Biased expression in Muscle (RPKM 828.), Heart (RPKM 47.) and 9 other tissues.

Summary

Predicted to enable RNA polymerase II complex binding activity; Histone Methyltransferase activity (H3-K36 specific); and p53 binding activity. Involved in heart development. Located in cytosol and nucleus. Orthologous to human SMYD2 (SET and MYND domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Smyd2 Products(1)

mRNA Protein Name
NM_206851.1 NP_996733.1 N-lysine methyltransferase SMYD2

Smyd2 Protein Structure

SET_SMYD2

SET_SMYD2: cd19202 (6 - 268)

zf-MYND

zf-MYND: pfam01753 (51 - 89)

TPR_10

TPR_10: pfam13374 (387 - 421)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 433 a.a.
Protein Preferred Names Protein Names

N-lysine methyltransferase SMYD2

SET and MYND domain-containing protein 2

histone methyltransferase SMYD2

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15226 AZ505 Inhibitor 99.99% Unkown
HY-19313 LLY-507 Inhibitor 98.28% Unkown
HY-19546 BAY-598 Inhibitor 99.30% Unkown
HY-134828 AZ506 Inhibitor 99.74% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smyd2 NCBI NCBI:56950