2. Gene
  3. Ctsk - cathepsin K Gene

Ctsk - cathepsin K Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 29175 | Gene type: protein coding

About Ctsk

Primary_assembly 2: 183,058,569-183,069,550 forward strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 240 orthologues, 27 paralogues and is associated with 16 phenotypes. Biased expression in Uterus (RPKM 264.), Testes (RPKM 141.3) and 9 other tissues.

Summary

Predicted to enable several functions, including collagen binding activity; fibronectin binding activity; and proteoglycan binding activity. Involved in bone resorption and intramembranous ossification. Located in extracellular space and lysosome. Biomarker of intracranial aneurysm and otitis media. Human ortholog(s) of this gene implicated in pycnodysostosis. Orthologous to human CTSK (Cathepsin K). [provided by Alliance of Genome Resources, Apr 2022]

Ctsk Products(1)

mRNA Protein Name
NM_031560.2 NP_113748.1 cathepsin K precursor

Ctsk Protein Structure

Inhibitor_I29

Inhibitor_I29: smart00848 (25 - 84)

Peptidase_C1

Peptidase_C1: pfam00112 (114 - 326)

  • 0
  • 100
  • 200
  • 300
  • 329 a.a.
Protein Preferred Names Protein Names

cathepsin K

Recombinant Ctsk Proteins

Cat. No. Product Name Accession Purity
HY-P72158 Cathepsin K Protein, Rat (His) O35186 (V115-M329) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-143714 Cathepsin K inhibitor 2 Inhibitor / Unkown
HY-155960 SH491 / Unkown
HY-RS03337 CTSK Human Pre-designed siRNA Set A / Unkown
HY-RS03338 Ctsk Mouse Pre-designed siRNA Set A / Unkown
HY-RS03339 Ctsk Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctsk NCBI NCBI:1513
Mus musculus Ctsk NCBI NCBI:13038