Dpp6 - dipeptidyl peptidase like 6 Gene

Also Known as DPP VI

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29272

Summary

Predicted to enable Potassium Channel regulator activity. Involved in positive regulation of potassium ion transport and positive regulation of protein localization to plasma membrane. Located in cell surface and neuronal cell body. Part of voltage-gated Potassium Channel complex. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; autosomal dominant non-syndromic intellectual disability 33; and spinal muscular atrophy. Orthologous to human DPP6 (Dipeptidyl Peptidase like 6). [provided by Alliance of Genome Resources, Apr 2022]

Dpp6 Products (1)

mRNA Protein Name
NM_022850.2 NP_074041.2 dipeptidyl aminopeptidase-like protein 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12575952 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of potassium ion transport IMP
IMP: Inferred from mutant phenotype
12575952 RGD
involved in positive regulation of protein localization to plasma membrane IDA
IDA: Inferred from direct assay
15671030 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
11173531 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
12575952 RGD
part of voltage-gated potassium channel complex IDA
IDA: Inferred from direct assay
12575952 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dipeptidyl aminopeptidase-like protein 6

  • DPPX

  • dipeptidyl aminopeptidase-related protein

  • dipeptidyl peptidase IV-like protein

  • dipeptidyl peptidase VI

  • dipeptidylpeptidase 6

  • dipeptidylpeptidase VI

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03966 DPP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21327 Dpp6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27846 Dpp6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dpp6 NCBI NCBI:1804