Rgs4 - regulator of G-protein signaling 4 Gene

Rattus norvegicus

Gene ID: 29480 | Gene type: protein coding

About Rgs4

Primary_assembly 13: 81,936,775-81,943,068 reverse strand.mRatBN7.2:CM026986.1

This gene has 3 transcripts (splice variants), 197 orthologues, 22 paralogues and is associated with 13 phenotypes. Biased expression in Brain (RPKM 76.9), Adrenal (RPKM 271.2) and 4 other tissues.

Summary

Enables G-protein alpha-subunit binding activity and GTPase activator activity. Involved in several processes, including regulation of ion transport; regulation of signal transduction; and response to alkaloid. Located in cytosol; nucleus; and plasma membrane. Part of protein-containing complex. Used to study epilepsy. Biomarker of bladder disease; hypertension; lesion of sciatic nerve; opioid abuse; and status epilepticus. Orthologous to human RGS4 (regulator of G protein signaling 4). [provided by Alliance of Genome Resources, Apr 2022]

Rgs4 Products(1)

mRNA	Protein	Name
NM_017214.2	NP_058910.1	regulator of G-protein signaling 4

Rgs4 Protein Structure

RGS_RGS4

0
100
205 a.a.

Protein Preferred Names

Protein Names

regulator of G-protein signaling 4

RGP4

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13509	CCG-50014	Inhibitor	99.42%	Unkown
HY-U00431	CCG 203769	Inhibitor	99.76%	Unkown
HY-70074	CCG-63802	Inhibitor	99.26%	Unkown
HY-110054	CCG-2046	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rgs4	NCBI	NCBI:5999

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