Smc3 - structural maintenance of chromosomes 3 Gene

Also Known as Cspg6; SMC-3; bamacan

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29486

Summary

Predicted to enable several functions, including beta-tubulin binding activity; cohesin loading activity; and dynein complex binding activity. Predicted to be involved in meiotic cell cycle; mitotic nuclear division; and regulation of DNA replication. Predicted to act upstream of or within stem cell population maintenance. Located in basement membrane. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 3. Orthologous to human SMC3 (structural maintenance of chromosomes 3). [provided by Alliance of Genome Resources, Apr 2022]

Smc3 Products (1)

mRNA Protein Name
NM_031583.2 NP_113771.2 structural maintenance of chromosomes protein 3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in meiotic cell cycle IEP
IEP: Inferred from expression pattern
10652260 RGD
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
9015313 RGD
located in synaptonemal complex IDA
IDA: Inferred from direct assay
10652260 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

structural maintenance of chromosomes protein 3

  • SMC protein 3

  • basement membrane chondroitin sulfate proteoglycan

  • basement membrane-associated chondroitin proteoglycan

  • chondroitin sulfate proteoglycan 6

  • chromosome segregation protein SmcD

  • structural maintenace of chromosomes 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150772 Tubulin/HDAC-IN-1 / Unkown
HY-158308 HDAC6-IN-41 Inhibitor / Unkown
HY-181024 PROTAC HDAC8 Degrader-4 Degrader / Unkown
HY-181979 HDAC8-IN-15 / Unkown
HY-182035 HDAC8-IN-16 / Unkown
HY-RS13419 SMC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18370 Smc3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24849 Smc3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smc3 NCBI NCBI:9126