Vtcn1 - V-set domain containing T cell activation inhibitor 1 Gene

Also Known as RGD1311204

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 295322

Summary

Predicted to enable signaling receptor binding activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; negative regulation of T cell proliferation; and negative regulation of apoptotic process. Predicted to act upstream of or within positive regulation of interleukin-2 production; regulation of T cell activation; and response to protozoan. Predicted to be anchored component of membrane. Predicted to be active in external side of plasma membrane. Orthologous to human VTCN1 (V-set domain containing T cell activation inhibitor 1). [provided by Alliance of Genome Resources, Apr 2022]

Vtcn1 Products (1)

mRNA Protein Name
NM_001024244.1 NP_001019415.1 V-set domain-containing T-cell activation inhibitor 1 precursor
Protein Preferred Names Protein Names

V-set domain-containing T-cell activation inhibitor 1

  • immune costimulatory protein B7-H4

Recombinant Vtcn1 Proteins

Cat. No. Product Name Accession Purity
HY-P75485 B7-H4 Protein, Rat (HEK293, His) Q501W4 (F29-S256) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Phase
HY-P990059 Puxitatug 99.00% Phase 3
HY-P990953 Zubotamig Inhibitor 96.46% Phase 2
HY-P990996 Felmetatug 99.00% Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15721 VTCN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17471 Vtcn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23929 Vtcn1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991703 Mocertatug Inhibitor 98% Unkown
HY-P990918 Emiltatug 99% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vtcn1 NCBI NCBI:79679