Copy Link Print Information

Zubotamig

(Synonyms: Gen1047)
Customer Review

Based on 1 Customer Validation

Zubotamig (Gen1047) is an CD3E/VTCN1-targeting Ig(G1 -κ_G1 -λ2) type chimeric human antibody. The recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001). Zubotamig induces T-cell mediated cytotoxicity of B7H4-positive tumor cells, triggers T-cell activation, and induces cytokine release from T cells in the presence of B7H4-expressing tumor cells. Zubotamig demonstrates antitumor activity in mouse patient-derived xenograft (PDX) models. Zubotamig can be used for the research of solid cancers (including breast, ovarian and lung cancer).

For research use only. We do not sell to patients.

  • Purity: 96.46%
  • CAS No.: 2640279-10-1
  • Molecular Weight:144.74 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Zubotamig
  • Experimental Validation Results for Zubotamig
  • Experimental Validation Results for Zubotamig
  • Zubotamig Chemical Structure
    Zubotamig Chemical Structure
CAS No.: 2640279-10-1
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Zubotamig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products
Keywords
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    IgG1-lambda-kappa

  • 1/16

    Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Zubotamig. The EC50 for this effect is 17.19 ng/mL.

  • 1/16

    Immobilized B7-H4 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78073) can bind Zubotamig. The EC50 for this effect is 29.2 ng/mL.

  • Zubotamig Chemical Structure
    1/16
  • Zubotamig
  • Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Zubotamig. The EC50 for this effect is 17.19 ng/mL.
  • Immobilized B7-H4 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78073) can bind Zubotamig. The EC50 for this effect is 29.2 ng/mL.
  • IgG1-lambda-kappa