Usp21 - ubiquitin specific peptidase 21 Gene

Also Known as Usp16; Usp23; ESTM28

Species: Mus musculus

Gene Type: protein coding
Gene ID: 30941

Summary

Enables thiol-dependent Deubiquitinase and transcription coactivator activity. Involved in histone deubiquitination and positive regulation of transcription, DNA-templated. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm. Is expressed in left lung; right lung; and submandibular gland primordium. Orthologous to human USP21 (ubiquitin specific peptidase 21). [provided by Alliance of Genome Resources, Apr 2022]

Usp21 Products (1)

mRNA Protein Name
NM_013919.4 NP_038947.2 ubiquitin carboxyl-terminal hydrolase 21

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables cysteine-type deubiquitinase activity IDA
IDA: Inferred from direct assay
18172164 MGI
enables cysteine-type peptidase activity IDA
IDA: Inferred from direct assay
18172164 MGI
enables transcription coactivator activity IDA
IDA: Inferred from direct assay
18172164 MGI
Biological Process GO Annotation Evidence References Source
involved in transcription initiation-coupled chromatin remodeling IDA
IDA: Inferred from direct assay
18172164 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 21

  • deubiquitinating enzyme 21

  • ubiquitin specific protease 21

  • ubiquitin specific protease 23

  • ubiquitin thioesterase 21

  • ubiquitin thiolesterase 21

  • ubiquitin-specific-processing protease 21

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13453 BAY 11-7082 Inhibitor 99.98% Unkown
HY-153045 BAY-805 Inhibitor 99.89% Unkown
HY-153045A BAY-728 99.92% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp21 NCBI NCBI:27005