Atf1 - activating transcription factor 1 Gene

Also Known as Atf-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 315305

Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including positive regulation of macromolecule biosynthetic process; positive regulation of neuron projection development; and response to cobalt ion. Located in nucleus. Part of transcription regulator complex. Biomarker of polycystic kidney disease. Orthologous to human ATF1 (activating transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Atf1 Products (1)

mRNA Protein Name
NM_001100895.1 NP_001094365.1 cyclic AMP-dependent transcription factor ATF-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
14576830 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
16373341 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
9489722 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
15084519 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA replication IMP
IMP: Inferred from mutant phenotype
11925444 RGD
involved in positive regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
9489722 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
17822438 RGD
involved in protein-containing complex assembly IMP
IMP: Inferred from mutant phenotype
10770487 RGD
involved in response to cobalt ion IEP
IEP: Inferred from expression pattern
10559391 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
10683356 RGD
Cellular Component GO Annotation Evidence References Source
part of transcription regulator complex IDA
IDA: Inferred from direct assay
14576830 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclic AMP-dependent transcription factor ATF-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103100 SB-699551 99.53% Unkown
HY-108618 BC11-38 Inhibitor 99.42% Unkown
HY-N12887 Mycothiazole Inhibitor / Unkown
HY-RS01127 ATF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05361 GDNF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-136700 SB-699551 free base / Unkown
HY-RS18337 Atf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24816 Atf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atf1 NCBI NCBI:466