2. Gene
  3. HPCAL1 - hippocalcin like 1 Gene

HPCAL1 - hippocalcin like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as BDR1; HLP2; VILIP-3

Gene ID: 3241 | Gene type: protein coding

About HPCAL1

Cytogenetic location: 2p25.1 Genomic coordinates (GRCh38): 2:10,302,904-10,427,604 (from NCBI)

This gene has 8 transcripts (splice variants), 216 orthologues and 14 paralogues. Ubiquitous expression in lung (RPKM 11.7), small intestine (RPKM 9.0) and 25 other tissues.

Summary

The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. It is highly similar to human hippocalcin protein and nearly identical to the rat and mouse hippocalcin like-1 proteins. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation and may be of relevance for neuronal signalling in the central nervous system. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2012]

HPCAL1 Products(5)

mRNA Protein Name
NM_001258357.2 NP_001245286.1 hippocalcin-like protein 1
NM_001258358.2 NP_001245287.1 hippocalcin-like protein 1
NM_001258359.2 NP_001245288.1 hippocalcin-like protein 1
NM_002149.4 NP_002140.2 hippocalcin-like protein 1
NM_134421.3 NP_602293.1 hippocalcin-like protein 1

HPCAL1 Protein Structure

EF-hand_7

EF-hand_7: EF-hand domain pair (40 - 86)

EF-hand_7

EF-hand_7: EF-hand domain pair (100 - 171)

  • 0
  • 100
  • 193 a.a.
Protein Preferred Names Protein Names

hippocalcin-like protein 1

calcium-binding protein BDR-1

Recombinant HPCAL1 Proteins

Cat. No. Product Name Accession Purity
HY-P70346 HLP2/HPCAL1 Protein, Human (His) P37235 (M1-F193) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06334 HPCAL1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus HPCAL1 VGNC VGNC:67636
Macaca mulatta HPCAL1 VGNC VGNC:73510
Rattus norvegicus HPCAL1 RGD RGD:708375
Canis familiaris HPCAL1 VGNC VGNC:41768
Bos taurus HPCAL1 VGNC VGNC:29937
Mus musculus HPCAL1 MGD MGI:1855689
Others HPCAL1 NCBI