Stim1 - stromal interaction molecule 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361618

Summary

Enables Calcium Channel regulator activity and store-operated Calcium Channel activity. Involved in activation of store-operated Calcium Channel activity; regulation of store-operated calcium entry; and store-operated calcium entry. Located in endoplasmic reticulum; growth cone; and plasma membrane. Used to study nephrogenic diabetes insipidus. Human ortholog(s) of this gene implicated in Stormorken syndrome; immunodeficiency 10; and tubular aggregate myopathy 1. Orthologous to human STIM1 (stromal interaction molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Stim1 Products (1)

mRNA Protein Name
NM_001108496.2 NP_001101966.2 stromal interaction molecule 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium channel regulator activity IMP
IMP: Inferred from mutant phenotype
21541286 RGD
enables store-operated calcium channel activity IMP
IMP: Inferred from mutant phenotype
21389210 RGD
Biological Process GO Annotation Evidence References Source
involved in activation of store-operated calcium channel activity IMP
IMP: Inferred from mutant phenotype
21541286 RGD
involved in regulation of store-operated calcium entry IMP
IMP: Inferred from mutant phenotype
22712562 RGD
involved in store-operated calcium entry IDA
IDA: Inferred from direct assay
27237974 RGD
involved in store-operated calcium entry IMP
IMP: Inferred from mutant phenotype
21389210 RGD
Cellular Component GO Annotation Evidence References Source
located in growth cone IDA
IDA: Inferred from direct assay
22712562 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

stromal interaction molecule 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-101942 Zegocractin Inhibitor 99.96% Phase 2

Pre-clinical Phase

Bioactive Molecules (18)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100001 SKF-96365 (hydrochloride) 99.93% Unkown
HY-100932 ML-9 Inhibitor 99.86% Unkown
HY-19408 Pyr10 Inhibitor 99.95% Unkown
HY-N1353 Rhamnocitrin Inhibitor 99.67% Unkown
HY-113618B RO2959 monohydrochloride Inhibitor 98.03% Unkown
HY-W099504 1-Heptanol 99.92% Unkown
HY-125942 SKF-96365 99.97% Unkown
HY-RS13913 STIM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-158990 GE1111 95.73% Unkown
HY-113618A RO2959 hydrochloride Inhibitor 99.12% Unkown
HY-100932A ML-9 Free Base Inhibitor / Unkown
HY-103071 GSK-5503A Inhibitor / Unkown
HY-181953 STIM1-TFR1-IN-1 Inhibitor / Unkown
HY-W099504S 1-Heptanol-d15 99.05% Unkown
HY-W099504S1 1-Heptanol-d7 / Unkown
HY-W099504S2 1-Heptanol-d1 / Unkown
HY-RS16865 Stim1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23306 Stim1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stim1 NCBI NCBI:6786