Macf1 - microtubule-actin crosslinking factor 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362587

Summary

Predicted to enable actin filament binding activity; microtubule minus-end binding activity; and structural molecule activity. Involved in positive regulation of Wnt signaling pathway. Located in membrane. Human ortholog(s) of this gene implicated in lissencephaly 9 with complex brainstem malformation. Orthologous to human MACF1 (microtubule actin crosslinking factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Macf1 Products (1)

mRNA Protein Name
NM_001135758.3 NP_001129230.2 microtubule-actin cross-linking factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16815997 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
16815997 RGD
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
16815997 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

microtubule-actin cross-linking factor 1

  • actin cross-linking family 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07942 MACF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22621 Macf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29136 Macf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Macf1 NCBI NCBI:23499