Osbp - oxysterol binding protein Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 365410

Summary

Predicted to enable several functions, including phosphatidylinositol-4-phosphate binding activity; sterol binding activity; and sterol transfer activity. Involved in positive regulation of Insulin secretion involved in cellular response to glucose stimulus; positive regulation of secretory granule organization; and positive regulation of tyrosine phosphorylation of STAT protein. Located in cytosol. Orthologous to human OSBP (oxysterol binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Osbp Products (1)

mRNA Protein Name
NM_001108927.2 NP_001102397.1 oxysterol-binding protein 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
29540530 RGD
involved in positive regulation of protein modification process IMP
IMP: Inferred from mutant phenotype
18230613 RGD
involved in positive regulation of secretory granule organization IMP
IMP: Inferred from mutant phenotype
29540530 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

oxysterol-binding protein 1

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17514 Itraconazole 99.59% Yes

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101213 OSW-1 Antagonist 99.66% Unkown
HY-17514S1 Itraconazole-d3 99.62% Unkown
HY-124806 TTP-8307 Inhibitor 99.90% Unkown
HY-17514S2 Itraconazole-d9 97.86% Unkown
HY-148391 23-Oxa-OSW-1 Inhibitor / Unkown
HY-156275 OSBP-IN-1 / Unkown
HY-178034 PROTAC OSBP Degrader-1 Degrader / Unkown
HY-178035 OSBP ligand-1 Inhibitor / Unkown
HY-178046 OSBP ligand-Linker Conjugate 1 Inhibitor / Unkown
HY-RS09835 OSBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09836 OSBP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-163891 Antifungal agent 107 Inhibitor / Unkown
HY-RS19928 Osbp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26430 Osbp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Osbp NCBI NCBI:5007