MEX3D - mex-3 RNA binding family member D Gene

Also Known as MEX3; TINO; RKHD1; MEX-3D; RNF193; OK/SW-cl.4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 399664

About MEX3D

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,554,672-1,568,325 (from NCBI)

This gene has 2 transcripts (splice variants), 167 orthologues and 3 paralogues. Broad expression in testis (RPKM 6.0), fat (RPKM 4.9) and 24 other tissues.

Summary

Enables mRNA 3'-UTR AU-rich region binding activity. Located in nucleus and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MEX3D Products (2)

mRNA Protein Name
NM_001174118.2 NP_001167589.1 RNA-binding protein MEX3D isoform 2
NM_203304.4 NP_976049.3 RNA-binding protein MEX3D isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA 3'-UTR AU-rich region binding IDA
IDA: Inferred from direct assay
14769789 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
14769789 GOA
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
14769789 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MEX3D Protein Structure

KH_1

KH_1: KH domain (181 - 240)

KH_1

KH_1: KH domain (275 - 334)

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (598 - 644)

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  • 651 a.a.
Protein Preferred Names Protein Names

RNA-binding protein MEX3D

  • RING finger and KH domain-containing protein 1

Related Diseases

Diseases Alias
Arthrogryposis, Distal, Type 5

  • Oculomelic Amyoplasia

  • Distal Arthrogryposis Type 5

  • Distal Arthrogryposis Type Iib

  • DA5

  • Arthrogryposis With Oculomotor Limitation And Electroretinal Abnormalities

  • Daiib

  • Distal Arthrogryposis Type 2b

  • Arthrogryposis-Oculomotor Limitation-Electroretinal Anomalies Syndrome

  • Distal Arthrogryposis With Ophthalmoplegia

  • Arthrogryposis- Oculomotor Limitation-Electroretinal Anomalies Syndrome

  • Arthrogryposis, Distal, Type Iib

  • Da2b

  • Freeman-Sheldon Syndrome Variant

  • Sheldon-Hall Syndrome

  • Arthogryposis With Oculomotor Limitation And Electroretinal Abnormalities

  • Arthrogryposis Ophthalmoplegia Retinopathy

  • Arthrogryposis, Distal, 5

  • Arthrogryposis, Distal, Type 2b
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08375 MEX3D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21644 Mex3d Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28162 Mex3d Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MEX3D RGD RGD:1310576
Mus musculus MEX3D MGD MGI:2681847
Bos taurus MEX3D VGNC VGNC:106821
Canis familiaris MEX3D VGNC VGNC:81279
Others MEX3D NCBI