TGFB1 - transforming growth factor beta 1 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 403998

About TGFB1

Primary_assembly 1: 113,219,701-113,241,694 forward strand.ROS_Cfam_1.0:CM025100.1

This gene has 4 transcripts (splice variants), 211 orthologues and 33 paralogues.

TGFB1 Products (2)

mRNA Protein Name
XM_038656895.1 XP_038512823.1 transforming growth factor beta-1 proprotein isoform X1
XM_038656896.1 XP_038512824.1 transforming growth factor beta-1 proprotein isoform X2

TGFB1 Protein Structure

TGFb_propeptide

TGFb_propeptide: pfam00688 (29 - 261)

TGF_beta_TGFB1

TGF_beta_TGFB1: cd19384 (292 - 390)

  • 0
  • 100
  • 200
  • 300
  • 391 a.a.
Protein Preferred Names Protein Names

transforming growth factor beta-1 proprotein

  • TGF-beta-1

  • transforming growth factor, beta 1 (Camurati-Engelmann disease)

Recombinant TGFB1 Proteins

Cat. No. Product Name Accession Purity
HY-P73617 TGF beta 1/TGFB1 Protein, Canine (HEK293, His) P54831 (L30-S390) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Phase
HY-P99305 Metelimumab Inhibitor 98.98% Phase 2
HY-P991382 SAR-439459 Inhibitor 99.41% Phase 2
HY-P991383 LY2382770 Inhibitor / Phase 2
HY-P991950 SHR-1906 Inhibitor / Phase 2

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14435 TGFB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W764758 3-OH-Kynurenamine dihydroiodide Activator 99.56% Unkown
HY-RS14436 Tgfb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-147195 QH536 Inhibitor / Unkown
HY-156908 3-OH-Kynurenamine Activator / Unkown
HY-RS14437 Tgfb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14438 TGFB1I1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174534 Human TGFB1 mRNA / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99606 Cirevetmab Inhibitor ≥99.0% Unkown
HY-P990517 Anti-TGFb1 Antibody Inhibitor 98.24% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TGFB1 NCBI NCBI:7040