MAS1 - MAS1 proto-oncogene, G protein-coupled receptor Gene

Homo sapiens

Also known as MAS; MGRA

Gene ID: 4142 | Gene type: protein coding

About MAS1

Cytogenetic location: 6q25.3 Genomic coordinates (GRCh38): 6:159,888,787-159,917,447 (from NCBI)

This gene has 2 transcripts (splice variants), 118 orthologues and 10 paralogues.

Summary

This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the Phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012]

MAS1 Products(2)

mRNA	Protein	Name
NM_001366704.2	NP_001353633.1	proto-oncogene Mas
NM_002377.4	NP_002368.1	proto-oncogene Mas

MAS1 Protein Structure

7tm_1

0
100
200
300
325 a.a.

Protein Preferred Names

Protein Names

proto-oncogene Mas

MAS1 oncogene

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08157	MAS1 Human Pre-designed siRNA Set A		/	Unkown
HY-RS08158	MAS1L Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	MAS1	VGNC	VGNC:74661
Felis catus	MAS1	VGNC	VGNC:68187
Rattus norvegicus	MAS1	RGD	RGD:3049
Mus musculus	MAS1	MGD	MGI:96918
Bos taurus	MAS1	VGNC	VGNC:31254
Others	MAS1	NCBI

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