Cd2 - Cd2 molecule Gene

Also Known as CD2R; LFA2; OX34; LFA-2; OX-34

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 497761

Summary

Enables identical protein binding activity; protein self-association; and receptor tyrosine kinase binding activity. Involved in T cell activation and cell-cell adhesion. Located in cell surface and membrane raft. Part of protein-containing complex. Orthologous to human CD2 (CD2 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd2 Products (1)

mRNA Protein Name
NM_012830.2 NP_036962.2 T-cell surface antigen CD2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
10526406 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9576909 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
1280324 RGD
enables receptor tyrosine kinase binding IPI
IPI: Inferred from physical interaction
18178839 RGD
Biological Process GO Annotation Evidence References Source
involved in cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
8938183 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
8938183 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
9576909 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

T-cell surface antigen CD2

  • CD2 antigen

  • LFA-3 receptor

  • OX-34 antigen

  • OX-45 surface antigen homolog to human T lymphocyte CD2 antigen

  • T-cell surface antigen T11/Leu-5

Recombinant Cd2 Proteins

Cat. No. Product Name Accession Purity
HY-P74322 CD2 Protein, Rat (HEK293, Fc) Q5I0M6 (R23-P202) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-158109 M3554 Inhibitor 98.74% Phase 1
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99904 Siplizumab Inhibitor 99.83% Phase 2

Pre-clinical Phase

Inhibitory Antibodies (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990868 Anti-CD2 Antibody (CB.219) Inhibitor 95.50% Unkown
HY-P991543 BTI-322 Inhibitor 98.15% Unkown
HY-P990286 Anti-Rat CD2 Antibody (OX-34) / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd2 NCBI NCBI:914