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Siplizumab

(Synonyms: MEDI-507; TCD601)
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Based on 1 Customer Validation

Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody against CD2. Siplizumab depletes T cells, decreases T cell activation, inhibites T cell proliferation and enriches naïve and bona fide regulatory T cells.

For research use only. We do not sell to patients.

  • Purity: 99.83%
  • CAS No.: 288392-69-8
  • Molecular Weight:146.25 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Siplizumab
  • Experimental Validation Results for Siplizumab
  • Experimental Validation Results for Siplizumab
  • Siplizumab Chemical Structure
  • Experimental Validation Results for Siplizumab
  • Experimental Validation Results for Siplizumab
  • Experimental Validation Results for Siplizumab
  • Siplizumab Chemical Structure
    Siplizumab Chemical Structure
CAS No.: 288392-69-8
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Human CD2 Protein (ECD, His Tag) can bind Siplizumab. The EC50 for this effect is 1.441 ng/mL.

  • 1/16

    Loaded Siplizumab on AHC2 biosensor, can bind CD2 Protein, Human (HEK293, His, HY-P7882) with an affinity constant of 3.775E-09 M as determined in BLI assay.

  • Siplizumab Chemical Structure
    1/16
  • Siplizumab
  • Immobilized Human CD2 Protein (ECD, His Tag) can bind Siplizumab. The EC50 for this effect is 1.441 ng/mL.
  • Loaded Siplizumab on AHC2 biosensor, can bind CD2 Protein, Human (HEK293, His, HY-P7882) with an affinity constant of 3.775E-09 M as determined in BLI assay.