DCUN1D1 - defective in cullin neddylation 1 domain containing 1 Gene

Homo sapiens

Also known as RP42; SCRO; Tes3; DCNL1; SCCRO; DCUN1L1

Gene ID: 54165 | Gene type: protein coding

About DCUN1D1

Cytogenetic location: 3q26.33 Genomic coordinates (GRCh38): 3:182,938,074-182,985,918 (from NCBI)

This gene has 8 transcripts (splice variants), 217 orthologues and 4 paralogues. Broad expression in testis (RPKM 16.2), bone marrow (RPKM 6.8) and 24 other tissues.

Summary

Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation and regulation of protein ubiquitination. Located in cytosol and nucleoplasm. Part of ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

DCUN1D1 Products(2)

mRNA	Protein	Name
NM_001308101.2	NP_001295030.1	DCN1-like protein 1 isoform 2
NM_020640.4	NP_065691.2	DCN1-like protein 1 isoform 1

DCUN1D1 Protein Structure

UBA_4

Cullin_binding

0
100
200
259 a.a.

Protein Preferred Names

Protein Names

DCN1-like protein 1

DCN1, defective in cullin neddylation 1, domain containing 1

Recombinant DCUN1D1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70093	DCN1-like protein 1/DCUN1D1 Protein, Human (His)	Q96GG9 (M1-V259)	≥95%

Related Diseases

Diseases

Alias

Squamous Cell Carcinoma

Epidermoid Carcinoma	Squamous Cell Cancer
Carcinoma, Squamous Cell	Squamous Cell Skin Cancer
Malignant Squamous Cell Tumor	Squamous Carcinoma
Squamous Cell Epithelioma	Carcinoma Squamous Cell
Neoplasms, Squamous Cell	Squamous Cell Carcinoma - Category
Malignant Squamous Cell Neoplasm	Squamous Cell Carcinoma Of Skin

Scrotum Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Scrotum

Scrotal Squamous Cell Carcinoma

Scrotal Carcinoma

Carcinoma Of Scrotum	Malignant Neoplasm Of Scrotum
Neoplasm Of Scrotum

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03598	DCUN1D1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	DCUN1D1	VGNC	VGNC:102688
Rattus norvegicus	DCUN1D1	RGD	RGD:1309668
Canis familiaris	DCUN1D1	VGNC	VGNC:39822
Bos taurus	DCUN1D1	VGNC	VGNC:27935
Mus musculus	DCUN1D1	MGD	MGI:2150386
Macaca mulatta	DCUN1D1	VGNC	VGNC:84194
Others	DCUN1D1	NCBI

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