CDIP1 - cell death inducing p53 target 1 Gene
Also Known as I1; CDIP; LITAFL; C16orf5
Species: Homo sapiens
Summary
Predicted to enable zinc ion binding activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Located in bounding membrane of organelle; centrosome; and nucleoplasm. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in brain (RPKM 37.0), kidney (RPKM 18.1) and 24 other tissues.
CDIP1 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001199054.2 | NP_001185983.1 | cell death-inducing p53-target protein 1 isoform a |
| NM_001199055.2 | NP_001185984.1 | cell death-inducing p53-target protein 1 isoform b |
| NM_001199056.2 | NP_001185985.1 | cell death-inducing p53-target protein 1 isoform c |
| NM_013399.3 | NP_037531.2 | cell death-inducing p53-target protein 1 isoform a |
| Molecular Function GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
21516116 | GOA |
| Biological Process GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator |
IMP
IMP: Inferred from mutant phenotype
|
17599062 | GOA |
| Cellular Component GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| located in cytoplasmic side of late endosome membrane |
IDA
IDA: Inferred from direct assay
|
27582497 | GOA |
| located in cytoplasmic side of lysosomal membrane |
IDA
IDA: Inferred from direct assay
|
27582497 | GOA |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
17599062 | GOA |
CDIP1 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Références |
|---|---|---|---|---|---|---|---|
|
Intra
|
CDIP1 | Q9H305 | EPN2 | Homo sapiens | O95208-2 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | EPN2 | Homo sapiens | O95208-2 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | UBC | Homo sapiens | P0CG48 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | UBC | Homo sapiens | P0CG48 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | TNIP1 | Homo sapiens | Q15025 | 25416956 | |
|
Intra
|
CDIP1 | Q9H305 | TNIP1 | Homo sapiens | Q15025 | 25416956 | |
|
Intra
|
CDIP1 | Q9H305 | UBB | Homo sapiens | P0CG47 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | UBB | Homo sapiens | P0CG47 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | OTUD7B | Homo sapiens | Q6GQQ9 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | OTUD7B | Homo sapiens | Q6GQQ9 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | UBQLN1 | Homo sapiens | Q9UMX0 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | UBQLN1 | Homo sapiens | Q9UMX0 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | UBQLN1 | Homo sapiens | Q9UMX0 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | UBQLN2 | Homo sapiens | Q9UHD9 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | UBQLN2 | Homo sapiens | Q9UHD9 | 32296183 | |
|
Intra
|
CDIP1 | Q9H305 | UBQLN2 | Homo sapiens | Q9UHD9 | 32296183 |