RAB20 - RAB20, member RAS oncogene family Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55647

About RAB20

This gene has 1 transcript (splice variant), 218 orthologues and 68 paralogues. Ubiquitous expression in spleen (RPKM 17.6), adrenal (RPKM 17.2) and 24 other tissues.

Summary

Predicted to enable GTPase activity. Involved in phagosome acidification and phagosome-lysosome fusion. Located in Golgi apparatus and phagocytic vesicle. [provided by Alliance of Genome Resources, Apr 2022]

RAB20 Products (1)

mRNA Protein Name
NM_017817.3 NP_060287.1 ras-related protein Rab-20

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Références Source
involved in phagosome acidification IMP
IMP: Inferred from mutant phenotype
21255211 GOA
involved in phagosome-lysosome fusion IMP
IMP: Inferred from mutant phenotype
21255211 GOA
Cellular Component GO Annotation Evidence Références Source
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
21255211 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAB20 Protein Structure

Ras

Ras: Ras family (7 - 199)

  • 0
  • 100
  • 200
  • 234 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-20

Related Diseases

Diseases Alias
Laryngeal Tuberculosis

  • Tuberculosis, Laryngeal
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS11530 RAB20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21711 Rab20 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28229 Rab20 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RAB20 VGNC VGNC:45260
Felis catus RAB20 VGNC VGNC:97583
Bos taurus RAB20 VGNC VGNC:33627
Mus musculus RAB20 MGD MGI:102789
Rattus norvegicus RAB20 RGD RGD:1593487
Macaca mulatta RAB20 VGNC VGNC:106287
Others RAB20 NCBI