Net1 - neuroepithelial cell transforming gene 1 Gene

Also Known as Net1a; mNET1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56349

Summary

Enables small GTPase binding activity. Acts upstream of or within myoblast migration and positive regulation of substrate adhesion-dependent cell spreading. Located in nucleus and plasma membrane. Is expressed in forelimb bud. Orthologous to human NET1 (neuroepithelial cell transforming 1). [provided by Alliance of Genome Resources, Apr 2022]

Net1 Products (2)

mRNA Protein Name
NM_001047159.2 NP_001040624.1 neuroepithelial cell-transforming gene 1 protein isoform 2
NM_019671.3 NP_062645.2 neuroepithelial cell-transforming gene 1 protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11350080 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within myoblast migration IGI
IGI: Inferred from genetic interaction
22987639 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuroepithelial cell-transforming gene 1 protein

  • Net1 homolog

  • guanine nucleotide regulatory protein (oncogene)

  • rho guanine nucleotide exchange factor 8

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-15472 PRX-08066 97.46% Phase 2
HY-15472A PRX-08066 maleate / Phase 2
HY-19471 (rac)-ZK-304709 / Phase 1

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09621 NTN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-131171 3β,5α-Tetrahydronorethisterone / Unkown
HY-RS09212 NET1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11209 PRPF38B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13306 SLC6A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13314 SLC6A5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15157 TSPAN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-172029 3,4-Methylenedioxy pyrovalerone metabolite 2 hydrochloride / Unkown
HY-RS18958 Net1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25448 Net1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Net1 NCBI NCBI:10276