SEMA3G - semaphorin 3G Gene

Also Known as sem2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56920

About SEMA3G

This gene has 3 transcripts (splice variants), 201 orthologues and 19 paralogues. Biased expression in fat (RPKM 51.5), placenta (RPKM 13.3) and 10 other tissues.

Summary

The transcription of this gene is activated by PPAR-gamma, and the resulting protein product plays a role in endothelial cell migration. Expression of this gene also inhibits tumor cell migration and invasion. [provided by RefSeq, Jul 2016]

SEMA3G Products (1)

mRNA Protein Name
NM_020163.3 NP_064548.1 semaphorin-3G precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SEMA3G Protein Structure

Sema

Sema: Sema domain (60 - 502)

PSI

PSI: Plexin repeat (521 - 550)

  • 0
  • 200
  • 400
  • 600
  • 782 a.a.
Protein Preferred Names Protein Names

semaphorin-3G

  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G

SEMA3G Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SEMA3G Q9NS98 DESI2 Homo sapiens Q9BSY9
Y2H Prey Pooling
32296183
Intra
SEMA3G Q9NS98 DESI2 Homo sapiens Q9BSY9
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Kallmann Syndrome

  • Hypogonadism With Anosmia

  • Kallman'S Syndrome

  • Anosmic Hypogonadism

  • Anosmic Idiopathic Hypogonadotropic Hypogonadism

  • Hypogonadotropic Hypogonadism And Anosmia

  • Hypogonadotropic Hypogonadism-Anosmia Syndrome

  • Olfacto-Genital Pathological Sequence

  • Familial Hypogonadism With Anosmia

  • Kallman Syndrome

  • Dysplasia Olfactogenitalis Of De Morsier

  • Kallmann'S Syndrome

  • Congenital Hypogonadotropic Hypogonadism With Anosmia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12656 SEMA3G Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21927 Sema3g Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28443 Sema3g Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SEMA3G MGD MGI:3041242
Bos taurus SEMA3G VGNC VGNC:34432
Rattus norvegicus SEMA3G RGD RGD:1306079
Felis catus SEMA3G VGNC VGNC:64991
Macaca mulatta SEMA3G VGNC VGNC:77345
Canis familiaris SEMA3G VGNC VGNC:45993
Others SEMA3G NCBI