IGSF9 - immunoglobulin superfamily member 9 Gene

Also Known as Nrt1; IGSF9A; FP18798

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57549

About IGSF9

Cytogenetic location: 1q23.2 Genomic coordinates (GRCh38): 1:159,927,041-159,945,613 (from NCBI)

This gene has 5 transcripts (splice variants), 121 orthologues and 36 paralogues. Biased expression in skin (RPKM 12.2), stomach (RPKM 7.5) and 8 other tissues.

Summary

Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to act upstream of or within dendrite development and regulation of synapse organization. Predicted to be located in dendrite and inhibitory synapse. Predicted to be integral component of membrane. Predicted to be active in axon and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

IGSF9 Products (2)

mRNA Protein Name
NM_001135050.2 NP_001128522.1 protein turtle homolog A isoform a precursor
NM_020789.4 NP_065840.2 protein turtle homolog A isoform b precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IGSF9 Protein Structure

I-set

I-set: Immunoglobulin I-set domain (136 - 223)

Ig_2

Ig_2: Immunoglobulin domain (227 - 319)

Ig_2

Ig_2: Immunoglobulin domain (329 - 402)

I-set

I-set: Immunoglobulin I-set domain (426 - 502)

fn3

fn3: Fibronectin type III domain (512 - 596)

fn3

fn3: Fibronectin type III domain (625 - 707)

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  • 1179 a.a.
Protein Preferred Names Protein Names

protein turtle homolog A

  • immunoglobulin superfamily member 9A

Related Diseases

Diseases Alias
Ovarian Endometrioid Stromal Sarcoma
Ovary Sarcoma

  • Sarcoma Of Ovary
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06652 IGSF9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06653 IGSF9B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20961 Igsf9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27478 Igsf9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris IGSF9 VGNC VGNC:41919
Rattus norvegicus IGSF9 RGD RGD:1304566
Bos taurus IGSF9 VGNC VGNC:30097
Mus musculus IGSF9 MGD MGI:2135283
Macaca mulatta IGSF9 VGNC VGNC:73620
Felis catus IGSF9 VGNC VGNC:97462
Others IGSF9 NCBI