Pidd1 - p53 induced death domain protein 1 Gene

Also Known as Lrdd; Pidd; 1200011D09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 57913

Summary

Predicted to enable endopeptidase activity. Acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process and extrinsic apoptotic signaling pathway via death domain receptors. Located in cytoplasm. Is expressed in brain; liver; nose; and urinary system. Orthologous to human PIDD1 (p53-induced death domain protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pidd1 Products (3)

mRNA Protein Name
NM_001360523.1 NP_001347452.1 p53-induced death domain-containing protein 1 isoform b
NM_001360524.1 NP_001347453.1 p53-induced death domain-containing protein 1 isoform b
NM_022654.2 NP_073145.1 p53-induced death domain-containing protein 1 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16183742 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process IGI
IGI: Inferred from genetic interaction
16183742 MGI
acts upstream of or within apoptotic signaling pathway IGI
IGI: Inferred from genetic interaction
16183742 MGI
acts upstream of or within extrinsic apoptotic signaling pathway IGI
IGI: Inferred from genetic interaction
16183742 MGI
acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors IGI
IGI: Inferred from genetic interaction
16183742 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16183742 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

p53-induced death domain-containing protein 1

  • leucine-rich and death domain containing

  • leucine-rich repeat and death domain-containing protein

  • p53 protein induced, with death domain

  • p53-induced protein with a death domain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10481 PIDD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21689 Pidd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28207 Pidd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pidd1 NCBI NCBI:55367