Il20 - interleukin 20 Gene

Also Known as If2d; Zcyto10

Species: Mus musculus

Gene Type: protein coding
Gene ID: 58181

Summary

Enables cytokine activity; interleukin-20 receptor binding activity; and interleukin-22 receptor binding activity. Acts upstream of or within positive regulation of osteoclast differentiation. Located in extracellular space. Is expressed in Harderian gland; ductus deferens; epididymis; prostate gland; and skin. Human ortholog(s) of this gene implicated in psoriasis. Orthologous to human IL20 (interleukin 20). [provided by Alliance of Genome Resources, Apr 2022]

Il20 Products (2)

mRNA Protein Name
NM_001311091.1 NP_001298020.1 interleukin-20 isoform 2
NM_021380.2 NP_067355.1 interleukin-20 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cytokine activity IDA
IDA: Inferred from direct assay
21844205 MGI
enables interleukin-20 receptor binding IDA
IDA: Inferred from direct assay
11470428 MGI
enables interleukin-20 receptor binding IPI
IPI: Inferred from physical interaction
21844205 MGI
enables interleukin-22 receptor binding IPI
IPI: Inferred from physical interaction
21844205 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
21844205 MGI
acts upstream of or within positive regulation of osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
21844205 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
21844205 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-20

  • IL-20

  • cytokine Zcyto10

  • four alpha helix cytokine ZCYTO10

  • four helix bundle cytokine 10

  • interferon 2d

Recombinant Il20 Proteins

Cat. No. Product Name Accession Purity
HY-P77963 IL-20 Protein, Mouse (HEK293, Fc) Q9JKV9 (L25-L176) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P77964 IL-20 Protein, Mouse (HEK293, His) Q9JKV9 (L25-L176) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P700198AF Animal-Free IL-20 Protein, Mouse (His) Q9JKV9 (L25-L176) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99198 Fletikumab Inhibitor 99.24% Phase 2

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-106647 Abacavir hydroxyacetate Inhibitor 99.61% Unkown
HY-175813 NPSR1 antagonist-1 / Unkown
HY-RS06698 IL17B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06731 IL20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06732 IL20RA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06733 IL20RB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174623 Human IL20RA mRNA / Unkown
HY-174624 Human IL20 mRNA / Unkown
HY-RS18136 Il20 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21870 Il20ra Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24611 Il20 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28387 Il20ra Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990016 Temtokibart Inhibitor 99.23% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il20 NCBI NCBI:50604