TLNRD1 - talin rod domain containing 1 Gene

Also Known as MESDC1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 59274

Summary

This gene encodes a protein that is regulated by micro RNA MiR-574-3, and is thought to have an oncogenic function in human Bladder Cancer. A similar gene in mouse is located in a chromosomal region critical for differentiation of mesoderm, which affects embryo patterning and the formation of heart, muscle, blood, skeleton and the urogenital system. The mouse gene is expressed in early development, and in the adult. [provided by RefSeq, Nov 2016]

TLNRD1 Products (1)

mRNA Protein Name
NG_052069.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TLNRD1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TLNRD1 Q9H1K6 ITGB1BP1 Homo sapiens O14713
Anti Tag CoIP
33961781
Intra
TLNRD1 Q9H1K6 TLNRD1 Homo sapiens Q9H1K6
Y2H Prey Pooling
32296183
Intra
TLNRD1 Q9H1K6 CCM2 Homo sapiens Q9BSQ5
Y2H Array
32296183
Intra
TLNRD1 Q9H1K6 KRIT1 Homo sapiens O00522
Anti Tag CoIP
33961781
Intra
TLNRD1 Q9H1K6 TLNRD1 Homo sapiens Q9H1K6
Validated Y2H
32296183
Intra
TLNRD1 Q9H1K6 SH2B2 Homo sapiens O14492-2
Y2H Prey Pooling
32296183
Intra
TLNRD1 Q9H1K6 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
TLNRD1 Q9H1K6 CCM2 Homo sapiens Q9BSQ5
Y2H Prey Pooling
32296183
Intra
TLNRD1 Q9H1K6 TLNRD1 Homo sapiens Q9H1K6
Y2H Array
32296183
Intra
TLNRD1 Q9H1K6 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
TLNRD1 Q9H1K6 SH2B2 Homo sapiens O14492-2
Y2H Array
32296183
Intra
TLNRD1 Q9H1K6 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
TLNRD1 Q9H1K6 CCM2 Homo sapiens Q9BSQ5
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15298 TXNRD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17152 Txnrd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23602 Txnrd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown