SECTM1 - secreted and transmembrane 1 Gene

Also Known as K12; SECTM

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6398

About SECTM1

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:82,321,024-82,333,959 (from NCBI)

This gene has 8 transcripts (splice variants) and 104 orthologues. Broad expression in small intestine (RPKM 29.2), duodenum (RPKM 20.3) and 17 other tissues.

Summary

This gene encodes a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein. It is found in a perinuclear Golgi-like pattern and thought to be involved in hematopoietic and/or immune system processes. [provided by RefSeq, Jul 2008]

SECTM1 Products (1)

mRNA Protein Name
NM_003004.3 NP_002995.1 secreted and transmembrane protein 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables receptor ligand activity IDA
IDA: Inferred from direct assay
10652336 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of T cell cytokine production IDA
IDA: Inferred from direct assay
22184754 GOA
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
9480746 GOA
is active in plasma membrane IDA
IDA: Inferred from direct assay
10652336 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

secreted and transmembrane protein 1

  • type 1a transmembrane protein

Recombinant SECTM1 Proteins

Cat. No. Product Name Accession Purity
HY-P71281 SECTM1 Protein, Human (HEK293, His) Q8WVN6 (Q29-G145) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P72032 SECTM1 Protein, Human (HEK293, hFc) Q8WVN6 (Q29-G145) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Ulceroglandular Tularemia
Corneal Dystrophy, Meesmann, 1

  • Meesmann Corneal Dystrophy

  • Mecd

  • Corneal Dystrophy, Meesmann Epithelial

  • Juvenile Hereditary Epithelial Dystrophy

  • Corneal Dystrophy, Juvenile Epithelial Of Meesmann

  • MECD1

  • Meesmann Corneal Dystrophy 1

  • Meesmann Corneal Epithelial Dystrophy

  • Meesmann Epithelial Corneal Dystrophy

  • Corneal Dystrophy, Juvenile Epithelial, Of Meesmann

  • Stocker-Holt Dystrophy

  • Meesman Dystrophy

  • Meesman'S Corneal Dystrophy

  • Juvenile Hereditary Epithelial Dystrophy Of Meesmann

  • Corneal Dystrophy, Meesmann 1

  • Juvenile Epithelial Corneal Dystrophy Of Meesmann

  • Mcd

  • Dystrophy, Corneal, Meesmann
Epithelial And Subepithelial Dystrophy
Familial Apolipoprotein C-Ii Deficiency

  • Familial Apoc-Ii Deficiency

  • Familial Apoc2 Deficiency

  • C-Ii Anapolipoproteinemia

  • Hyperlipoproteinemia, Type 1b

  • Hyperlipoproteinemia, Type Ib

  • Hyperlipoproteinemia Type I
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12628 SECTM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SECTM1 RGD RGD:735132
Mus musculus SECTM1 MGD MGI:2384805
Others SECTM1 NCBI