Naaa - N-acylethanolamine acid amidase Gene

Also Known as Asahl; 2210023K21Rik; 3830414F09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67111

Summary

Predicted to enable N-(long-chain-acyl)ethanolamine deacylase activity; N-acylsphingosine amidohydrolase activity; and fatty acid amide hydrolase activity. Predicted to be involved in several processes, including N-acylethanolamine metabolic process; N-acylphosphatidylethanolamine metabolic process; and sphingosine metabolic process. Predicted to act upstream of or within lipid catabolic process. Located in lysosome. Is expressed in future brain and ventricular layer. Orthologous to human NAAA (N-acylethanolamine acid amidase). [provided by Alliance of Genome Resources, Apr 2022]

Naaa Products (2)

mRNA Protein Name
NM_001163687.1 NP_001157159.1 N-acylethanolamine-hydrolyzing acid amidase isoform 2 precursor
NM_025972.4 NP_080248.2 N-acylethanolamine-hydrolyzing acid amidase isoform 1 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in lysosome IDA
IDA: Inferred from direct assay
29514215 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-acylethanolamine-hydrolyzing acid amidase

  • ASAH-like protein

  • acylsphingosine deacylase NAAA

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0182 Carmofur Inhibitor 99.95% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-121975 N-Cyclohexanecarbonylpentadecylamine 98.68% Phase 1

Pre-clinical Phase

Bioactive Molecules (17)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W074890 Palmitoylglycine Modulator 99.84% Unkown
HY-145339 ARN19702 Inhibitor 99.69% Unkown
HY-120813 ARN 077 Inhibitor 99.82% Unkown
HY-124597 ARN726 Inhibitor 98.10% Unkown
HY-185011 AM9053 98.36% Unkown
HY-147773 NAAA-IN-1 Inhibitor 99.65% Unkown
HY-147775 NAAA-IN-3 Inhibitor 98.20% Unkown
HY-120813A ARN 077 (enantiomer) 99.40% Unkown
HY-132882 ARN19689 Inhibitor / Unkown
HY-125384 ARN14686 / Unkown
HY-157223 ARN16186 Inhibitor / Unkown
HY-D2338 PMBD / Unkown
HY-N15826 RBM1-151 Substrate / Unkown
HY-RS08993 NAAA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-169834 NAAA-IN-6 Inhibitor / Unkown
HY-RS18776 Naaa Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25264 Naaa Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Naaa NCBI NCBI:27163