Ido2 - indoleamine 2,3-dioxygenase 2 Gene
Also Known as IDO-2; Indol1
Species: Rattus norvegicus
About Ido2
This gene has 1 transcript (splice variant), 91 orthologues and is associated with 3 phenotypes. Restricted expression toward (RPKM 55.6).
Summary
Predicted to enable indoleamine 2,3-dioxygenase activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in 'de novo' NAD biosynthetic process from tryptophan and tryptophan catabolic process to kynurenine. Predicted to be active in cytoplasm. Orthologous to human IDO2 (indoleamine 2,3-dioxygenase 2). [provided by Alliance of Genome Resources, Apr 2022]
Ido2 Products (8)
| mRNA | Protein | Name |
|---|---|---|
| XM_039095218.1 | XP_038951146.1 | indoleamine 2,3-dioxygenase 2 isoform X4 |
| XM_008771375.2 | XP_008769597.2 | indoleamine 2,3-dioxygenase 2 isoform X1 |
| XM_039095217.1 | XP_038951145.1 | indoleamine 2,3-dioxygenase 2 isoform X3 |
| XM_039095215.1 | XP_038951143.1 | indoleamine 2,3-dioxygenase 2 isoform X2 |
| XM_039095215.1 | XP_038951143.1 | indoleamine 2,3-dioxygenase 2 isoform X2 |
| XM_008771375.2 | XP_008769597.2 | indoleamine 2,3-dioxygenase 2 isoform X1 |
| XM_039095218.1 | XP_038951146.1 | indoleamine 2,3-dioxygenase 2 isoform X4 |
| XM_039095217.1 | XP_038951145.1 | indoleamine 2,3-dioxygenase 2 isoform X3 |
Ido2 Protein Structure
IDO: pfam01231 (14 - 398)
- 0
- 100
- 200
- 300
- 405 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
indoleamine 2,3-dioxygenase 2 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-100687 | GNF-PF-3777 | Inhibitor | 98.03% | Unkown |
| HY-145280 | IDO1/2-IN-1 | Inhibitor | 98.06% | Unkown |
| HY-151093 | IDO2-IN-1 | Inhibitor | 98.10% | Unkown |
| HY-112867 | Amg-1 | Inhibitor | / | Unkown |
| HY-184078 | 8-F-2-(Me-Pip-Me)-Tryptanthrin | Inhibitor | / | Unkown |
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