KLF9 - KLF transcription factor 9 Gene

Also Known as BTEB; BTEB1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 687

About KLF9

Cytogenetic location: 9q21.12 Genomic coordinates (GRCh38): 9:70,384,604-70,414,657 (from NCBI)

This gene has 1 transcript (splice variant), 196 orthologues and 22 paralogues. Ubiquitous expression in fat (RPKM 44.7), gall bladder (RPKM 34.1) and 25 other tissues.

Summary

The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter. Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription. [provided by RefSeq, Jul 2008]

KLF9 Products (1)

mRNA Protein Name
NM_001206.4 NP_001197.1 Krueppel-like factor 9

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to cortisol stimulus IDA
IDA: Inferred from direct assay
22711835 GOA
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
22711835 GOA
involved in negative regulation of keratinocyte proliferation IMP
IMP: Inferred from mutant phenotype
22711835 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
22711835 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KLF9 Protein Structure

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (159 - 186)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (190 - 212)

  • 0
  • 100
  • 200
  • 244 a.a.
Protein Preferred Names Protein Names

Krueppel-like factor 9

  • BTE-binding protein 1

Related Diseases

Diseases Alias
Otosclerosis

  • Otospongiosis
Endometrial Cancer

  • Endometrial Carcinoma

  • Endometrial Neoplasm

  • Malignant Neoplasm Of Endometrium

  • Endometrioid Carcinoma

  • Endometrial Neoplasms

  • Carcinoma, Endometrioid

  • Endometrial Cancer, Familial

  • Endometrial Carcinoma, Somatic

  • Endometrial Cancer, Susceptibility To

  • Endometrial Ca

  • Malignant Endometrial Neoplasm

  • Neoplasm Of Endometrium

  • Primary Malignant Neoplasm Of Endometrium

  • Tumor Of Endometrium

  • Carcinoma Of The Endometrium

  • Endometrioid Carcinoma Of Female Reproductive System

  • ENDMC

  • Carcinoma Endometrioid

  • Endometrial Cancers

  • Cancer, Endometrial

  • Uterine Corpus Cancer
Familial Thyroid Dyshormonogenesis

  • Thyroid Dyshormonogenesis

  • Familial Dyshormonogenetic Goiter
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07346 KLF9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21360 Klf9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27879 Klf9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus KLF9 RGD RGD:70934
Felis catus KLF9 VGNC VGNC:102943
Canis familiaris KLF9 VGNC VGNC:53731
Mus musculus KLF9 MGD MGI:1333856
Bos taurus KLF9 VGNC VGNC:30632
Others KLF9 NCBI