A1cf - APOBEC1 complementation factor Gene

Also Known as ASP; Acf; MCM; mer; ACF64; ACF65; MerCreMer; 1810073H04Rik; 9130016M20Rik; alpha-MHC-MerCreMer; alphaMHC-Cre-Mer-Cre; Tg(Myh6-cre/Esr1*)1Jmk

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69865

Summary

Predicted to enable mRNA binding activity and single-stranded RNA binding activity. Acts upstream of or within RNA modification; embryo implantation; and mRNA localization resulting in posttranscriptional regulation of gene expression. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; gonad; olfactory epithelium; and trigeminal ganglion. Human ortholog(s) of this gene implicated in gout. Orthologous to human A1CF (APOBEC1 complementation factor). [provided by Alliance of Genome Resources, Apr 2022]

A1cf Products (2)

mRNA Protein Name
NM_001081074.2 NP_001074543.1 APOBEC1 complementation factor isoform 1
NM_001365078.1 NP_001352007.1 APOBEC1 complementation factor isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24916387 MGI
Biological Process GO Annotation Evidence References Source
involved in cytidine to uridine editing IDA
IDA: Inferred from direct assay
30309881 MGI
acts upstream of or within cytidine to uridine editing IGI
IGI: Inferred from genetic interaction
24916387 MGI
acts upstream of or within embryo implantation IMP
IMP: Inferred from mutant phenotype
16055734 MGI
acts upstream of or within mRNA localization resulting in post-transcriptional regulation of gene expression IGI
IGI: Inferred from genetic interaction
20541607 MGI
acts upstream of or within mRNA modification IGI
IGI: Inferred from genetic interaction
20541607 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
20541607 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20541607 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

APOBEC1 complementation factor

  • APOBEC-1 stimulating protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00009 A1CF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22090 A1cf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens A1cf NCBI NCBI:29974