Phf19 - PHD finger protein 19 Gene

Also Known as 3110009G19Rik; 3321402G02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74016

Summary

Enables methylated histone binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of histone H3-K27 methylation; and stem cell population maintenance. Part of ESC/E(Z) complex. Is expressed in brain ventricular layer; early conceptus; eye; genitourinary system; and intestine. Orthologous to human PHF19 (PHD finger protein 19). [provided by Alliance of Genome Resources, Apr 2022]

Phf19 Products (1)

mRNA Protein Name
NM_028716.4 NP_082992.1 PHD finger protein 19

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables methylated histone binding IDA
IDA: Inferred from direct assay
23104054 MGI
Biological Process GO Annotation Evidence References Source
involved in epigenetic regulation of gene expression IMP
IMP: Inferred from mutant phenotype
22438827 MGI
involved in negative regulation of gene expression, epigenetic IMP
IMP: Inferred from mutant phenotype
23104054 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
23104054 MGI
involved in stem cell differentiation IMP
IMP: Inferred from mutant phenotype
23104054 MGI
involved in stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
22438827 MGI
Cellular Component GO Annotation Evidence References Source
part of ESC/E(Z) complex IDA
IDA: Inferred from direct assay
22438827 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PHD finger protein 19

  • polycomb-like protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-181914 UNC7242 Antagonist / Unkown
HY-RS10419 PHF19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22723 Phf19 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29237 Phf19 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Phf19 NCBI NCBI:26147