PGBD5 - piggyBac transposable element derived 5 Gene

Homo sapiens

Gene ID: 79605 | Gene type: protein coding

About PGBD5

Cytogenetic location: 1q42.13 Genomic coordinates (GRCh38): 1:230,314,490-230,426,332 (from NCBI)

This gene has 3 transcripts (splice variants) and 202 orthologues. Biased expression in brain (RPKM 13.1), adrenal (RPKM 4.4) and 9 other tissues.

Summary

The piggyBac family of proteins, found in diverse Animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. [provided by RefSeq, May 2010]

PGBD5 Products(1)

mRNA	Protein	Name
NM_001258311.2	NP_001245240.1	piggyBac transposable element-derived protein 5

PGBD5 Protein Structure

DDE_Tnp_1_7

0
100
200
300
400
455 a.a.

Protein Preferred Names

Protein Names

piggyBac transposable element-derived protein 5

piggyBac domain related protein 5

Related Diseases

Diseases

Alias

Glioblastoma Proneural Subtype

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10379	PGBD5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	PGBD5	VGNC	VGNC:100033
Bos taurus	PGBD5	VGNC	VGNC:32784
Mus musculus	PGBD5	MGD	MGI:2429955
Rattus norvegicus	PGBD5	RGD	RGD:1310825
Canis familiaris	PGBD5	VGNC	VGNC:44455
Felis catus	PGBD5	VGNC	VGNC:64121

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