2. Gene
  3. ELMO3 - engulfment and cell motility 3 Gene

ELMO3 - engulfment and cell motility 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CED12; CED-12; ELMO-3

Gene ID: 79767 | Gene type: protein coding

About ELMO3

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,199,131-67,204,004 (from NCBI)

This gene has 6 transcripts (splice variants), 207 orthologues and 5 paralogues. Broad expression in duodenum (RPKM 15.2), skin (RPKM 12.9) and 20 other tissues.

Summary

The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq, Jul 2008]

ELMO3 Products(1)

mRNA Protein Name
NM_024712.5 NP_078988.3 engulfment and cell motility protein 3

ELMO3 Protein Structure

DUF3361

DUF3361: Domain of unknown function (DUF3361) (168 - 322)

ELMO_CED12

ELMO_CED12: ELMO/CED-12 family (343 - 522)

  • 0
  • 200
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  • 773 a.a.
Protein Preferred Names Protein Names

engulfment and cell motility protein 3

ced-12 homolog 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04313 ELMO3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ELMO3 MGD MGI:2679007
Felis catus ELMO3 VGNC VGNC:61817
Rattus norvegicus ELMO3 RGD RGD:1304734
Canis familiaris ELMO3 VGNC VGNC:40311
Macaca mulatta ELMO3 VGNC VGNC:72060
Bos taurus ELMO3 VGNC VGNC:28440