ELMO3 - engulfment and cell motility 3 Gene

Also Known as CED12; CED-12; ELMO-3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79767

About ELMO3

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,199,131-67,204,004 (from NCBI)

This gene has 6 transcripts (splice variants), 207 orthologues and 5 paralogues. Broad expression in duodenum (RPKM 15.2), skin (RPKM 12.9) and 20 other tissues.

Summary

The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. [provided by RefSeq, Jul 2008]

ELMO3 Products (1)

mRNA Protein Name
NM_024712.5 NP_078988.3 engulfment and cell motility protein 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24567399 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ELMO3 Protein Structure

DUF3361

DUF3361: Domain of unknown function (DUF3361) (168 - 322)

ELMO_CED12

ELMO_CED12: ELMO/CED-12 family (343 - 522)

  • 0
  • 200
  • 400
  • 600
  • 773 a.a.
Protein Preferred Names Protein Names

engulfment and cell motility protein 3

  • ced-12 homolog 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04313 ELMO3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ELMO3 MGD MGI:2679007
Felis catus ELMO3 VGNC VGNC:61817
Rattus norvegicus ELMO3 RGD RGD:1304734
Canis familiaris ELMO3 VGNC VGNC:40311
Macaca mulatta ELMO3 VGNC VGNC:72060
Bos taurus ELMO3 VGNC VGNC:28440
Others ELMO3 NCBI