MAP3K19 - mitogen-activated protein kinase kinase kinase 19 Gene

Homo sapiens

Also known as RCK; YSK4

Gene ID: 80122 | Gene type: protein coding

About MAP3K19

This gene has 22 transcripts (splice variants), 195 orthologues and 35 paralogues. Biased expression in testis (RPKM 2.7), lung (RPKM 0.8) and 1 other tissue.

Summary

Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]

MAP3K19 Products(7)

mRNA	Protein	Name
NM_001018044.3	NP_001018054.1	mitogen-activated protein kinase kinase kinase 19 isoform 3
NM_001018046.3	NP_001018056.1	mitogen-activated protein kinase kinase kinase 19 isoform 2
NM_001018047.3	NP_001018057.1	mitogen-activated protein kinase kinase kinase 19 isoform 4
NM_001282883.2	NP_001269812.1	mitogen-activated protein kinase kinase kinase 19 isoform 5
NM_001321177.2	NP_001308106.1	mitogen-activated protein kinase kinase kinase 19 isoform 6
NM_001400438.1	NP_001387367.1	mitogen-activated protein kinase kinase kinase 19 isoform 1
NM_025052.5	NP_079328.3	mitogen-activated protein kinase kinase kinase 19 isoform 1

MAP3K19 Protein Structure

Pkinase

0
300
600
900
1200
1328 a.a.

Protein Preferred Names

Protein Names

mitogen-activated protein kinase kinase kinase 19

SPS1/STE20-related protein kinase YSK4

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-145409	SR-0813	Inhibitor	99.93%	Unkown
HY-RS08053	MAP3K19 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	MAP3K19	VGNC	VGNC:97206
Bos taurus	MAP3K19	VGNC	VGNC:31194
Macaca mulatta	MAP3K19	VGNC	VGNC:81460
Mus musculus	MAP3K19	MGD	MGI:1203481
Felis catus	MAP3K19	VGNC	VGNC:80274
Rattus norvegicus	MAP3K19	RGD	RGD:1566400
Others	MAP3K19	NCBI

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