Nell2 - neural EGFL like 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81734

Summary

Enables heparin binding activity; identical protein binding activity; and protein kinase C binding activity. Involved in several processes, including development of secondary female sexual characteristics; neuron cellular homeostasis; and positive regulation of hormone secretion. Located in several cellular components, including dendrite; extracellular space; and perikaryon. Orthologous to human NELL2 (neural EGFL like 2). [provided by Alliance of Genome Resources, Apr 2022]

Nell2 Products (1)

mRNA Protein Name
NM_031070.3 NP_112332.2 protein kinase C-binding protein NELL2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heparin binding IDA
IDA: Inferred from direct assay
10548494 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
10548494 RGD
enables protein kinase C binding IDA
IDA: Inferred from direct assay
10600492 RGD
Biological Process GO Annotation Evidence References Source
involved in development of secondary female sexual characteristics IMP
IMP: Inferred from mutant phenotype
18547942 RGD
involved in neurogenesis IMP
IMP: Inferred from mutant phenotype
32597395 RGD
involved in neuron cellular homeostasis IDA
IDA: Inferred from direct assay
12941464 RGD
involved in positive regulation of hormone secretion IMP
IMP: Inferred from mutant phenotype
18547942 RGD
involved in regulation of growth IDA
IDA: Inferred from direct assay
10548494 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17196548 RGD
located in dendrite IDA
IDA: Inferred from direct assay
10548494 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
10548494 RGD
located in perikaryon IDA
IDA: Inferred from direct assay
10548494 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein kinase C-binding protein NELL2

  • NEL-like 2

  • NEL-like protein 2

  • rCG50753-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09205 NELL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19465 Nell2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25958 Nell2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nell2 NCBI NCBI:4753