St13 - ST13, Hsp70 interacting protein Gene
Species: Rattus norvegicus
Summary
Enables several functions, including HSP70 protein binding activity; chaperone binding activity; and dATP binding activity. Involved in chaperone cofactor-dependent protein refolding and negative regulation of protein refolding. Located in cytosol. Part of protein-containing complex. Orthologous to several human genes including ST13 (ST13 HSP70 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]
St13 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_031122.2 | NP_112384.1 | hsc70-interacting protein |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables Hsp70 protein binding |
IDA
IDA: Inferred from direct assay
|
7585962 | RGD |
| enables Hsp70 protein binding |
IPI
IPI: Inferred from physical interaction
|
9528774 | RGD |
| enables dATP binding |
IDA
IDA: Inferred from direct assay
|
9183013 | RGD |
| enables identical protein binding |
IPI
IPI: Inferred from physical interaction
|
7585962 | RGD |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
21808025 | RGD |
| enables protein domain specific binding |
IDA
IDA: Inferred from direct assay
|
7585962 | RGD |
| enables protein domain specific binding |
IPI
IPI: Inferred from physical interaction
|
9528774 | RGD |
| enables protein-containing complex binding |
IDA
IDA: Inferred from direct assay
|
7585962 | RGD |
| enables protein-folding chaperone binding |
IPI
IPI: Inferred from physical interaction
|
9528774 | RGD |
| enables unfolded protein binding |
IDA
IDA: Inferred from direct assay
|
9183013 | RGD |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in chaperone cofactor-dependent protein refolding |
IDA
IDA: Inferred from direct assay
|
7585962 | RGD |
| involved in negative regulation of protein refolding |
IDA
IDA: Inferred from direct assay
|
9183013 | RGD |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of protein-containing complex |
IDA
IDA: Inferred from direct assay
|
7585962 | RGD |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
hsc70-interacting protein |
|
|
St13 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
St13 | P50503 | Esr1 | Rattus norvegicus | P06211 | 21808025 | |
|
Intra
|
St13 | P50503 | St13 | Rattus norvegicus | P50503 | 23812373 | |
|
Intra
|
St13 | P50503 | St13 | Rattus norvegicus | P50503 | 23812373 | |
|
Intra
|
St13 | P50503 | Bag1 | Rattus norvegicus | B0K019 | 21808025 |