2. Gene
  3. Il23a - interleukin 23, alpha subunit p19 Gene

Il23a - interleukin 23, alpha subunit p19 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p19; IL-23

Gene ID: 83430 | Gene type: protein coding

About Il23a

Chromosome 10: 128,132,008-128,134,621 reverse strand.GRCm39:CM001003.3

This gene has 2 transcripts (splice variants), 96 orthologues and is associated with 30 phenotypes. Low expression observed in reference dataset.

Summary

Contributes to interleukin-23 receptor binding activity. Involved in positive regulation of defense response to virus by host; positive regulation of immune response; and positive regulation of neutrophil chemotaxis. Acts upstream of or within T cell proliferation and positive regulation of transcription by RNA polymerase II. Located in extracellular space. Part of interleukin-23 complex. Is expressed in decidua; decidua basalis; embryo; and extraembryonic component. Orthologous to human IL23A (interleukin 23 subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il23a Products(1)

mRNA Protein Name
NM_031252.2 NP_112542.1 interleukin-23 subunit alpha precursor

Il23a Protein Structure

IL23

IL23: pfam16649 (27 - 184)

  • 0
  • 100
  • 196 a.a.
Protein Preferred Names Protein Names

interleukin-23 subunit alpha

IL-23 subunit alpha

IL-23-A

IL-23p19

interleukin-23 subunit p19

Recombinant Il23a Proteins

Cat. No. Product Name Accession Purity
HY-P70421 IL-23 alpha (175a.a) & IL-12 beta (313a.a) Heterodimer Protein, Mouse (Sf9) Q9EQ14 (V22-A196)&P43432 (M23-S335 ) ≥95%
HY-P70604 IL-23 alpha (175a.a) & IL-12 beta (313a.a) Heterodimer Protein, Mouse (HEK293, C-His) Q9EQ14 (V22-A196)&P43432 (M23-S335) ≥95%
HY-P70709 IL-23 alpha (175a.a) & IL-12 beta (313a.a) Heterodimer Protein, Mouse (HEK293) Q9EQ14 (V22-A196)&P43432 (M23-S335) ≥95%
HY-P77705 IL-23 alpha (175a.a) & IL-12 beta (313a.a) Heterodimer Protein, Mouse (HEK293, N-His) Q9EQ14 (V22-A196)&P43432 (M23-S335) ≥95%
HY-P78152 IL-23 alpha Protein, Mouse (Biotinylated, HEK293, His-Avi) Q9EQ14 (V22-A196) ≥95%
HY-P74814 IL-23 alpha (175a.a) & IL-12 beta (313a.a) Heterodimer Protein, Mouse (HEK293, His) Q9EQ14 (V22-A196)&P43432 (M23-S335) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N10295 Flavipin Agonist / Unkown
HY-RS06739 IL23A Human Pre-designed siRNA Set A / Unkown
HY-RS06740 Il23a Mouse Pre-designed siRNA Set A / Unkown
HY-RS06741 Il23a Rat Pre-designed siRNA Set A / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990057 Picankibart Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il23a NCBI NCBI:51561