CCDC3 - coiled-coil domain containing 3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83643

About CCDC3

This gene has 2 transcripts (splice variants) and 198 orthologues. Broad expression in skin (RPKM 47.2), fat (RPKM 42.7) and 21 other tissues.

Summary

Involved in negative regulation of gene expression; negative regulation of lipid metabolic process; and negative regulation of tumor necrosis factor-mediated signaling pathway. Located in endoplasmic reticulum and extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

CCDC3 Products (2)

mRNA Protein Name
NM_001282658.2 NP_001269587.1 coiled-coil domain-containing protein 3 isoform 2
NM_031455.4 NP_113643.1 coiled-coil domain-containing protein 3 isoform 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in negative regulation of lipid metabolic process IDA
IDA: Inferred from direct assay
28827783 GOA
involved in negative regulation of tumor necrosis factor-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
25193116 GOA
involved in signal transduction IDA
IDA: Inferred from direct assay
28827783 GOA
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
28827783 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coiled-coil domain-containing protein 3

  • fat/vessel-derived secretory protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02042 CCDC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CCDC3 VGNC VGNC:38832
Mus musculus CCDC3 MGD MGI:1921436
Rattus norvegicus CCDC3 RGD RGD:1559473
Macaca mulatta CCDC3 VGNC VGNC:70842
Felis catus CCDC3 VGNC VGNC:83517
Others CCDC3 NCBI