Gpr6 - G protein-coupled receptor 6 Gene

Rattus norvegicus

Gene ID: 83683 | Gene type: protein coding

About Gpr6

Primary_assembly 20: 44,489,853-44,492,624 reverse strand.mRatBN7.2:CM026993.1

This gene has 1 transcript (splice variant), 186 orthologues and 18 paralogues. Restricted expression toward (RPKM 28.1).

Summary

Predicted to enable sphingosine-1-phosphate receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human GPR6 (G protein-coupled receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Gpr6 Products(1)

mRNA	Protein	Name
NM_031806.2	NP_113994.1	G-protein coupled receptor 6

Gpr6 Protein Structure

7tm_GPCRs

0
100
200
300
363 a.a.

Protein Preferred Names

Protein Names

G-protein coupled receptor 6

putative G protein-coupled receptor (CNL3)

sphingosine 1-phosphate receptor GPR6

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-134661A	CVN424		99.70%	Phase 2

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-134661	(S)-CVN424		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Gpr6	NCBI	NCBI:2830

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