Gpr6 - G protein-coupled receptor 6 Gene
Species: Rattus norvegicus
About Gpr6
This gene has 1 transcript (splice variant), 186 orthologues and 18 paralogues. Restricted expression toward (RPKM 28.1).
Summary
Predicted to enable sphingosine-1-phosphate receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human GPR6 (G protein-coupled receptor 6). [provided by Alliance of Genome Resources, Apr 2022]
Gpr6 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_031806.2 | NP_113994.1 | G-protein coupled receptor 6 |
Gpr6 Protein Structure
7tm_GPCRs: cl28897 (73 - 340)
7tm_GPCRs: cd14964 (75 - 99)
7tm_GPCRs: cd14964 (108 - 129)
7tm_GPCRs: cd14964 (142 - 164)
7tm_GPCRs: cd14964 (187 - 203)
7tm_GPCRs: cd14964 (223 - 246)
7tm_GPCRs: cd14964 (278 - 300)
7tm_GPCRs: cd14964 (308 - 333)
- 0
- 100
- 200
- 300
- 363 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
G-protein coupled receptor 6 |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-134661A | Solangepras | 99.70% | Phase 3 |
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-134661 | (S)-CVN424 | 99.16% | Unkown | |
| HY-182011 | GPR6 inverse agonist 2 | Agonist | / | Unkown |
| HY-181349 | GPR6 inverse agonist 1 | Agonist | / | Unkown |
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